Clarke first exhibited with the Royal Hibernian Academy in 1913, and would go on to exhibit over 60 artworks in the forty years until 1953, the majority being portraits.
Amongst the portrait commissions Clarke received were ones for Dermod O’Brien, President Éamon de Valera, Archbishop McQuaid, and Lennox Robinson.
Clarke spent a great deal of time on the Aran Islands with fellow artist Seán Keating and her husband, from which she produced a number of landscapes and smaller studies.
